Acepromazine inhibits hERG potassium ion channels expressed in human embryonic kidney 293 cells
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Acepromazine inhibits hERG potassium ion channels expressed in human embryonic kidney 293 cells
The effects of acepromazine on human ether-à-go-go-related gene (hERG) potassium channels were investigated using whole-cell voltage-clamp technique in human embryonic kidney (HEK293) cells transfected with hERG. The hERG currents were recorded with or without acepromazine, and the steady-state and peak tail currents were analyzed for the evaluating the drug effects. Acepromazine inhibited the ...
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ژورنال
عنوان ژورنال: The Korean Journal of Physiology & Pharmacology
سال: 2017
ISSN: 1226-4512,2093-3827
DOI: 10.4196/kjpp.2017.21.1.75